>A US study on rats found that tumours became more responsive to the drug tamoxifen with the addition of fish oil to their diets.

Researchers concluded that omega-3 fatty acids found in the fish oil could prove to be a safe and beneficial booster for tamoxifen therapy.

Tamoxifen blocks the female hormone oestrogen’s ability to fuel breast cancer.

Rats with breast cancer were fed either a 17% fish oil diet or a 20% corn oil diet for eight weeks. In each case the oil supplement was given with or without tamoxifen.

Analysis of the tumours showed that omega-3 fatty acids in the fish oil increased the activity of genes promoting cellular specialisation, or differentiation.

This indicates an anti-cancer effect, since cancer cells are highly undifferentiated.

Combining fish oil and tamoxifen also reduced the activity of genes linked to tumour growth and cancer spread.

Study leader Dr Jose Russo, director of the Breast Cancer Research Laboratory at Fox Chase Cancer Center Philadelphia, said: “If a tumour was being treated with tamoxifen, the addition of an omega-3 fatty acid diet seemed to make the tumour, at least at the molecular level, more benign and less aggressive and responsive to tamoxifen.”

The findings were presented at the annual meeting of the American Association for Cancer Research in Orlando, Florida.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s